DEVELOPMENT OF BIOSENSOR SYSTEMS FOR EARLY DIAGNOSIS OF CHRONIC DISEASES IN UKRAINE

Abstract

The relevance of this study is driven by the need within the Ukrainian healthcare system for technologies capable of detecting chronic diseases at preclinical stages, when biochemical changes are minimal and traditional laboratory methods show insufficient sensitivity and delayed result acquisition. The purpose of the article is to provide a scientific rationale for the principles of designing and implementing biosensor systems that can enable early detection of chronic diseases in Ukraine and enhance the effectiveness of the diagnostic process across different levels of medical care. The research methods included analytical generalization of current technical solutions in biosensing, analysis of sensitivity and stability parameters of sensor platforms, assessment of the prerequisites for their digital integration into the medical infrastructure, and a structural-functional examination of barriers to their development in Ukrainian conditions. The results demonstrate that the key technical and biomedical parameters determining the sensitivity and accuracy limits of biosensor systems have been identified. The study reveals the conditions that ensure effective integration of these systems into primary care, telemedicine services, and laboratory workflows. It also shows that the development of sensor technologies in Ukraine is constrained by the shortage of high-tech materials, the absence of adapted calibration standards, and the fragmented nature of the innovation infrastructure. Recommendations have been formulated regarding the design of modular sensor platforms, improvement of digital compatibility, implementation of phased clinical testing, and expansion of service support. The conclusions indicate that biosensor systems are a critically important tool for improving the effectiveness of early diagnosis, but their broad application in Ukraine is possible only with technological standardization, digital integration, and the development of a local material and technical base. Future research should focus on developing more stable receptor materials, implementing advanced signal processing algorithms, establishing national validation standards, and creating a comprehensive manufacturing infrastructure for biosensor technologies.